双联抗血小板治疗对后循环缺血性脑卒中的疗效

The Effect of Dual Antiplatelet Therapy on Ischemic Stroke in Posterior Circulation

摘要:

〔摘 要〕 目的：观察双联抗血小板治疗对后循环缺血性脑卒中的疗效。方法：选取新密市第一人民医院 2018 年 8 月至 2019年8月收治的56例后循环缺血性脑卒患者为研究对象，按照治疗方案不同将患者分为对照组（28例：单一应用阿司匹林） 与观察组（28 例：阿司匹林、氯吡格雷双联抗血小板治疗），比较两组患者预后情况。结果：观察组患者持续用药 1 周后、 持续用药 3 周后美国国立卫生研究院卒中量表（NIHSS）评分均低于对照组，且观察组患者持续用药 3 周后血小板、血纤 维蛋白原等凝血因子各项参数均优于对照组，差异均具有统计学意义（P ＜ 0.05）。结论：后循环缺血性脑卒中患者阿司 匹林、氯吡格雷双联抗血小板治疗效果明显优于单一应用阿司匹林治疗效果。

Abstract:

〔Abstract〕 Objective To observe the effect of dual antiplatelet therapy on posterior circulation ischemic stroke. Methods A total of 56 patients with posterior circulation ischemic stroke admitted to Xinmi First People's Hospital from August 2018 to August 2019 were selected as the research objects, and the patients were divided into control groups according to different treatment options (28 cases: single Application of aspirin) and observation group (28 cases: aspirin, clopidogrel dual antiplatelet therapy), compare the prognosis of the two groups of patients. Results The scores of the National Institutes of Health Stroke Scale (NIHSS) of the observation group after 1 week of continuous medication and 3 weeks of continuous medication were lower than those of the control group, and the observation group had platelets, fibrinogen, etc. after 3 weeks of continuous medication The parameters of coagulation factors were better than those of the control group, and the differences were statistically significant (P < 0.05). Conclusion The effect of aspirin and clopidogrel dual antiplatelet therapy in patients with posterior circulation ischemic stroke is significantly better than that of aspirin alone.