强力定眩片联合倍他司汀治疗眩晕患者临床疗效

Clinical Effect of Strong Dingxuan Tablets Combined with Betahistine in the Treatment of Vertigo

摘要:

〔摘 要〕 目的：分析在眩晕患者中采取强力定眩片联合倍他司汀治疗方案，对其脑血流动力学水平、不良反应以 及临床疗效的影响。方法：选取福建省级机关医院 2021 年 4 月至 2022 年 4 月期间收治的 88 例因眩晕接受治疗的患者， 按照随机数表法分为对照组与观察组，各 44 例。对照组患者采取倍他司汀单一治疗，观察组患者采取强力定眩片联 合倍他司汀治疗，记录两组患者脑后循环血流动力学水平，统计不良反应发生情况。结果：治疗后观察组患者的基底 动脉（BA）、左椎动脉（LVA）、右椎动脉（RVA）均高于对照组，差异具有统计学意义（P ＜ 0.05）。两组患者不 良反应发生率比较，差异无统计学意义（P ＞ 0.05）。观察组患者治疗总有效率为 97.73 %，高于对照组的 77.27 %， 差异具有统计学意义（P ＜ 0.05）。结论：应用倍他司汀治疗眩晕的同时联合强力定眩片，可以在保证治疗安全性的 前提下，更好地改变患者的血流动力学水平，提高疗效。

Abstract:

〔Abstract〕 Objective To analyze the effect of strong Dingxuan tablets combined with betahistine on cerebral hemodynamics, adverse reactions and clinical efficacy in patients with vertigo. Methods A total of 88 patients who received treatment for vertigo in Fujian Provincial Hospital from April 2021 to April 2022 were selected and divided into a control group and an observation group according to the random number table method, with 44 cases in each group. The patients in the control group were treated with betahistine alone, and the patients in the observation group were treated with strong Dingxuan tablets combined with betahistine. The hemodynamic levels of posterior cerebral circulation in the two groups were recorded, and the occurrence of adverse reactions was counted. Results After treatment, the basilar artery (BA), left vertebral artery (LVA) and right vertebral artery (RVA) of the observation group were higher than those of the control group, and the differences were statistically significant (P < 0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups (P > 0.05). The total effective rate of the observation group was 97.73 %, which was higher than 77.27 % of the control group, and the difference was statistically significant (P < 0.05). Conclusion The application of betahistine in the treatment of vertigo combined with strong Dingxuan tablets can better change the hemodynamic level of patients and improve the efficacy on the premise of ensuring the safety of treatment.