Abstract:〔Abstract〕 Objective To investigate the early visual quality of femtosecond laser small incision lenticule extraction (SMILE) in patients over 40 years of age. Methods A prospective study was conducted on 28 patients (56 eyes) with moderate and low degree myopia who received SMILE in the ophthalmology department of The First People's Hospital of Zhaoqing from November 2020 to December 2021. Uncorrected visual acuity (UCVA), spherical lens degree, column lens degree, intraocular pressure, astigmatism, coma, clover difference, spherical aberration, high-order aberration, wavefront aberration, and Steller were measured in all patients before and after surgery at 1 day, 1 week, 1 month, and 3 months, respectively, and visual quality was assessed before and after surgery.Results After surgery, the UCVA at 1 day, 1 week, 1 month and 3 months was higher than before surgery, and the bulb degree, column degree and intraocular pressure were lower than those before surgery, the differences were statistically significant (P < 0.05). After surgery, the astigmatism at 1 month and 3 months was lower than before surgery, and the difference of coma, spherical aberration, high-order aberration and wavefront aberration were higher than those before surgery, the differences were statistically significant (P < 0.05). 3 months after surgery, the total scores of environmental triggers, visual function, ocular symptoms and visual quality questionnaire were lower than those before surgery, the differences were statistically significant (P < 0.05). Conclusion SMILE surgery is safe and effective for people over 40 years old, and the adjustment will affect the satisfaction of near vision. Adequate preoperative communication is the key to improve satisfaction.