南平市高尿酸血症及痛风的发病现状及影响因素分析

Analysis on the Status Quo and Influencing Factors of Hyperuricemia and Gout in Nanping City

摘要:

〔摘 要〕 目的：分析南平市高尿酸血症及痛风的发病现状及影响因素。 方法：选择 2020 年 5 月至 2022 年 1 月于 南平市建阳中医院健康体检者3253名作为研究对象，采用全自动生化分析仪测定研究对象尿酸水平，结合其典型症状、 体征及影像学检查，根据检查结果统计高尿酸血症及痛风的发生率，并将健康体检者分为发生组与未发生组。查阅两组 的临床资料，采用单因素和多因素 logistic 回归分析可能导致高尿酸血症及痛风发生的因素。 结果：3253 名健康体检 者中，发生高尿酸血症及痛风 242 名，发生率为 7.44 %。多因素 logistic 回归分析结果显示：患有高血压、吸烟饮酒、 每日饮水量＜ 1000 mL、偶尔运动或不运动、低总蛋白均为健康体检人群中高尿酸血症及痛风发病的危险因素；而偶 尔食用蘑菇及木耳为健康体检人群中高尿酸血症及痛风发病的保护因素。 结论：南平市健康体检人群中高尿酸血症及 痛风发病率较高，且受到高血压、吸烟饮酒、偶尔食用蘑菇及木耳、每日饮水量、运动情况、总蛋白等因素的影响， 应根据可能的影响因素采取相应的措施干预，降低高尿酸血症及痛风发生率。

Abstract:

〔Abstract〕 Objective To analyze the current situation and influencing factors of hyperuricemia and gout in Nanping. Methods 3253 health examinees from Nanping Jianyang Hospital of Traditional Chinese Medicine from May 2020 to January 2022 were selected as the study subjects. Uric acid level of the subjects was measured by automatic biochemical analyzer, combined with their typical symptoms, signs and imaging examination, and the incidence of hyperuricemia and gout were counted according to the examination results, and the health examinees were divided into occurrence group and non-occurrence group. The clinical data of the two groups were reviewed, and the factors that might lead to hyperuricemia and gout were analyzed by single factor and multiple factor logistic regression. Results Of the 3253 health examinees, 242 had hyperuricemia and gout, with an incidence of 7.44 %. Multivariate logistic regression analysis showed that high blood pressure, smoking and drinking, daily water consumption < 1000 mL, occasional exercise or no exercise, and low total protein were all risk factors for hyperuricemia and gout in healthy people; The occasional diet of mushrooms and agaric is the protective factor of hyperuricemia and gout in the health examination population. Conclusion The incidence rate of hyperuricemia and gout among the health examination population in Nanping is high, and is affected by hypertension, smoking and drinking, occasional eating mushrooms and agaric, daily drinking water, exercise, total protein and other factors. Corresponding measures should be taken according to the possible influencing factors to reduce the incidence of hyperuricemia and gout.