Abstract:〔Abstract〕 Objective To investigate the computed tomography (CT) and magnetic resonance imaging (MRI) findings of Lemmel syndrome. Methods Five patients with Lemmel syndrome confirmed by endoscopic retrograde cholangio pancreatography (ERCP) were collected, and the imaging findings were retrospectively analyzed. Results Among the 5 patients with Lemmel syndrome, the lesions were all obstructive jaundice caused by periampullary diverticula (PAD). CT showed diverticulum in descending segment of duodenum with dilatation, and the lower end of common bile duct was compressed, causing obstruction and dilation of common bile duct. Enhanced scan showed that diverticulum was consistent with duodenum enhancement, diverticulum mucosa was enhanced, and diverticulitis was changed; magnetic resonance cholangiopancreatography (MRCP) can clearly show the degree of intrahepatic and extrahepatic bile duct dilatation and the relationship between the common bile duct and diverticulum. Conclusion The imaging manifestations of Lemmel syndrome have certain characteristics, which are crucial for the etiological treatment of obstructive jaundice.