Abstract:〔Abstract〕 Objective To investigate the effect of information case management in the postoperative extended care of patients with high myopia after femtosecond laser small incision lenticule extraction (SMILE). Methods A total of 86 patients with high myopia who underwent femtosecond laser SMILE treated in Shenzhen Eye Hospital from January 2022 to December 2022 were selected as the study objects, and were divided into a control group and an observation group by random number table method, with 43 cases in each group. Patients in the control group were treated with conventional extended care mode, and patients in the observation group were treated with information case management based on the conventional extended care mode. The anxiety, depression, self-care ability and nursing satisfaction of the two groups were compared. Results After 1 month of follow-up, the scores of self-rating anxiety scale (SAS) and self-rating depression scale (SDS) in the observation group were lower than those in the control group, and the scores of exercise of self-care agency scale (ESCA) were higher than those in the control group, with statistical significance (P < 0.05). After 1 month of follow-up, the nursing satisfaction of patients in the observation group was higher than that in the control group, and the difference was statistically significant (P < 0.05). Conclusion Information case management can provide accurate extended care services for patients with high myopia after operation with femtosecond laser SMILE, promote patients' eye health and mental health after operation, and thus improve patients' prognosis.